Science & Research Careers at Lifespan

Research Scientist Job

Job Number: TMH17280

Job Title: Research Scientist

Department: 2MINF Kurpewski HCC - 7861024

Facility: The Miriam Hospital

Location: Providence, RI

•PhD in molecular biology or similar
•Knowledge of computer word processing, spreadsheet and database applications
•Expertise in phylogeny, bioinformatics, computer science and/or statistics desired
•Professional post-graduate research experience desired
•While most duties are performed in an office environment, incumbent is exposed to patient-care environment. Any risk of exposure to contagious or noxious elements is minimized by adherence to safety procedures and protocols. Normal office environment. Requires standing, bending and sitting. Sufficient visual acuity and manual dexterity to use laboratory equipment, computer keyboard and other common office equipment.
•Ability to train, work with and supervise students, laboratory staff and collaborators on projects and assays
•Experience with initiation, validation and maintaining laboratory assays and experiments such as partial and full genome sequencing, HIV drug resistance testing, molecular epidemiology and tropism, including established and novel techniques. This may involve application of working protocols as well as design of new ones
•Prior extensive experience in laboratory research, including research techniques such as RNA and DNA extraction, primer design, PCR amplification and purification, Sanger sequencing, Next Generation Sequencing, sequence assembly, sequence editing and base calling, assay troubleshooting, site-directed mutagenesis, cloning, single genome sequencing, real time PCR, filter paper analytes

Under the general supervision of the Principal Investigator, and within established policies and procedures, conducts experiments and analyses and performs scientific investigative research in biomedical areas related to patient care; participates in the design of experimental protocols and research directions and develops new experimental protocols and procedures to carry out established research objectives and allow quantitative and qualitative evaluation and interpretation of data obtained; executes existing protocols and develops new experimental methodologies to carry out established research objectives; collects and analyzes data using bioinformatics, phylogenetic and statistical methodology and software; participates in the interpretation of the results through discussions with the principal investigator and other collaborators to review data compared to hypotheses and research methodology in instances of inexplicable data; researches literature in the field pertaining to the research; writes presentations, manuscripts and grants in line with the research goals and based on the research performed; and performs other duties as assigned.
•Ability to be responsible for all laboratory-related procedures, activities and maintenance, as associated with current and planned research projects
•Performs independently within department policies and practices and under the supervision of the principal investigator. Refers specific complex problems to supervisor where clarification of departmental policies and procedures may be required.

•Communicate and work with research collaborators and the research-team personnel, locally, nationally and internationally
•Interact with laboratory and analytical personnel in result implementation and research collaboration
•International experience and ability to travel desired
•Knowledge of computer database design and applications desired
•Knowledge of and experience with computer programming related to bioinformatics, sequence alignment, drug resistance interpretation, protein structure, databases, phylogenetics, molecular evolution and/or statistics desired
•Although variable and depending on specific tasks, it is estimated that 50% of the time will be spent on laboratory duties and 50% on other research duties